3rd User Account with Admin won't Run Applications

[ChuckR]

I set up a new User Account with Admin Authority. Originally, I have 2. The new account gives me the message

"Your Internet Security Setting prevented one or more files from being opened" when I try and run an application.

More Weirdness. I reset IE11 with NO LUCK. I tried running C:\Windows\explorer.exe under RUN with NO LUCK.

Weird, Under Run I CLICKED BROWSE and sure enough Windows Explorer opened. From this I SHOULD be able to execute any programs.
NEVER HAPPENED. NOTHING EXECUTES.

I went back to NewQ id and tried to run CCleaner, Firefox whose icons had been setup as part of the install.

I get the same STUPID message about "Your Internet Security Setting prevented one or more files from being opened".

[ChuckR]

Doing a Restore before some System activity, freed the profile the new and old Userid's had. The new Userid seems to work fine.